Membrane proteins

The expanding family of natural anion channelrhodopsins reveals large variations in kinetics, conductance, and spectral sensitivity

A notable variant, designated “ZipACR”, is particularly promising for inhibitory optogenetics because of its combination of larger current amplitudes than those of previously reported ACRs and an unprecedentedly fast conductance cycle.

Elena G Govorunova, Oleg A Sineshchekov, Elsa M Rodarte, Roger Janz, Olivier Morelle, Michael Melkonian, Gane K-S Wong, John L Spudich